Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 10/20 | 0.64 |
| ▸ | DBF4 | Q9UBU7 | 10/20 | 0.64 |
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20893822 | 0.88 | CDC7 (0.66) | CDC7DBF4TRPM8LMNAKDM4E | |
| SCHEMBL29631123 | 0.88 | CDC7 (0.66) | CDC7DBF4TRPM8LMNAKDM4E | |
| SCHEMBL3080219 | 0.86 | CDC7 (0.63) | CDC7DBF4TRPM8LMNAKDM4E | |
| SCHEMBL290384 | 0.84 | CDC7 (0.75) | CDC7DBF4TRPM8LMNAKDM4E | |
| SCHEMBL25407669 | 0.83 | CDC7 (0.59) | CDC7DBF4TRPM8LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL28885517 | 0.83 | CDC7 (0.73) | CDC7DBF4TRPM8LMNAKDM4E | |
| Bromide SCHEMBL28376005 | 0.83 | CDC7 (0.73) | CDC7DBF4TRPM8LMNAKDM4E | |
| SCHEMBL892889 | 0.82 | CDC7 (0.77) | CDC7DBF4TRPM8LMNAKDM4E | |
| SCHEMBL12186978 | 0.82 | CDC7 (0.64) | CDC7DBF4TRPM8LMNAKDM4E | |
| SCHEMBL28297246 | 0.82 | CDC7 (0.71) | CDC7DBF4TRPM8LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |