Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 4/20 | 0.44 |
| ▸ | ACHE | P22303 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29817790 | 0.97 | KDM4E (0.61) | KDM4EALDH1A1SMN1; SMN2HSD17B10BCHE | |
| SCHEMBL29817801 | 0.96 | SMN1; SMN2 (0.62) | KDM4EALDH1A1SMN1; SMN2HSD17B10BCHE | |
| SCHEMBL29817795 | 0.88 | HSD17B10 (0.54) | KDM4EALDH1A1SMN1; SMN2HSD17B10BCHE | |
| SCHEMBL29817900 | 0.88 | HSD17B10 (0.54) | KDM4EALDH1A1SMN1; SMN2HSD17B10BCHE | |
| SCHEMBL29817787 | 0.88 | HSD17B10 (0.51) | KDM4EALDH1A1SMN1; SMN2HSD17B10BCHE | |
| SCHEMBL29817632 | 0.86 | HSD17B10 (0.58) | KDM4EALDH1A1SMN1; SMN2HSD17B10BCHE | |
| SCHEMBL29817655 | 0.86 | HSD17B10 (0.58) | KDM4EALDH1A1SMN1; SMN2HSD17B10BCHE | |
| SCHEMBL29817659 | 0.85 | HSD17B10 (0.51) | KDM4EALDH1A1SMN1; SMN2HSD17B10BCHE | |
| SCHEMBL29817763 | 0.85 | HSD17B10 (0.56) | KDM4EALDH1A1SMN1; SMN2HSD17B10BCHE | |
| SCHEMBL29817752 | 0.85 | HSD17B10 (0.53) | KDM4EALDH1A1SMN1; SMN2HSD17B10BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022161556-A1 | TACRINE DERIVATIVES POSSESSING DUAL ACTIVITY AND THEIR USE | FAKULTNI NEMOCNICE HRADEC KRALOVE (CZ) | 2022-08-04 | — | — | WO | disclosed |