SCHEMBL29823660

SCHEMBL29823660

N[C@@H](CCC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 2/20 0.43
▸ FABP5 Q01469 3/20 0.38
▸ CASP3 P42574 2/20 0.38
▸ FABP7 O15540 2/20 0.38
▸ EPHX2 P34913 1/20 0.36
▸ MDM4 O15151 2/20 0.36
▸ TP53 P04637 2/20 0.36
▸ TLR2 O60603 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29823996 0.89 KMT2A (0.45) KMT2AFABP5CASP3FABP7EPHX2
SCHEMBL15424391 0.83 KMT2A (0.50) KMT2AFABP5CASP3FABP7EPHX2
SCHEMBL15223383 0.81 KMT2A (0.45) KMT2AFABP5CASP3FABP7EPHX2
SCHEMBL29401774 0.79 TLR2 (0.55) KMT2ACASP3MDM4TP53TLR2
SCHEMBL29750297 0.79 TLR2 (0.55) KMT2ACASP3MDM4TP53TLR2
SCHEMBL31217659 0.79 TLR2 (0.55) KMT2ACASP3MDM4TP53TLR2
SCHEMBL29651368 0.79 TLR2 (0.55) KMT2ACASP3MDM4TP53TLR2
SCHEMBL1755686 0.79 TLR2 (0.55) KMT2ACASP3MDM4TP53TLR2
SCHEMBL13227676 0.79 TLR2 (0.55) KMT2ACASP3MDM4TP53TLR2
SCHEMBL29350848 0.79 TLR2 (0.55) KMT2ACASP3MDM4TP53TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12617819-B2 Intermediate used for biologically active polypeptide and method for preparing same HANMI FINE CHEMICAL CO., LTD. (KR) 2026-05-05 — — US disclosed
US-20220242913-A1 NOVEL INTERMEDIATE USED FOR BIOLOGICALLY ACTIVE POLYPEPTIDE AND METHOD FOR PREPARING SAME HANMI FINE CHEMICAL CO., LTD. (KR) 2022-08-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220242913-A1 NOVEL INTERMEDIATE USED FOR BIOLOGICALLY ACTIVE POLYPEPTIDE AND METHOD FOR PREPARING SAME VIP, IAPP, ANPEP KMT2A 4831/4885FABP5 1686/4885CASP3 4410/4885
US-12617819-B2 Intermediate used for biologically active polypeptide and method for preparing same VIP, PTMS, HM13 KMT2A 3953/4885FABP5 4405/4885CASP3 3781/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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