Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 5/20 | 0.40 |
| ▸ | HTR2B | P41595 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | NMT1 | P30419 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30740685 | 0.77 | GBA1 (0.43) | HTR2CSLC6A4SLC6A2SLC6A3HTR6 | |
| SCHEMBL29825954 | 0.77 | MEN1 (0.47) | — | |
| SCHEMBL29994671 | 0.76 | HRH1 (0.62) | HRH1HTR2CHTR2BSLC6A4SLC6A2 | |
| SCHEMBL8358502 | 0.76 | HRH1 (0.62) | HRH1HTR2CHTR2BSLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL70482 | 0.74 | HRH1 (0.61) | HRH1HTR2CHTR2BSLC6A4SLC6A2 | |
| SCHEMBL30740706 | 0.71 | GSK3B (0.32) | HTR2CHTR1A | |
| SCHEMBL5369456 | 0.70 | HTR2C (0.51) | HRH1HTR2CHTR2BSLC6A4HTR6 | |
| SCHEMBL29994691 | 0.70 | HRH1 (0.62) | HRH1HTR2CHTR2BSLC6A4SLC6A2 | |
| SCHEMBL2300978 | 0.70 | HRH1 (0.62) | HRH1HTR2CHTR2BSLC6A4SLC6A2 | |
| SCHEMBL30740728 | 0.69 | CYP1A2 (0.35) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4284795-A1 | GPCR RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE | Carmot Therapeutics, Inc. (US) | 2023-12-06 | — | — | EP | disclosed |
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |
| WO-2022165076-A1 | GPCR RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE | CARMOT THERAPEUTICS, INC. (US) | 2022-08-04 | — | — | WO | disclosed |