Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 12/20 | 0.35 |
| ▸ | MTOR | P42345 | 3/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SGK1 | O00141 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21596703 | 1.00 | CYP2C9 (0.36) | CYP2C9PIK3CAMTORPIK3R1ALDH1A1 | |
| SCHEMBL29829446 | 0.94 | PIK3CA (0.38) | CYP2C9PIK3CAMTORPIK3R1ALDH1A1 | |
| SCHEMBL23610291 | 0.94 | PIK3CA (0.38) | CYP2C9PIK3CAMTORPIK3R1ALDH1A1 | |
| SCHEMBL21596662 | 0.92 | CYP2C9 (0.34) | CYP2C9PIK3CAMTORPIK3R1CYP3A4 | |
| SCHEMBL29829592 | 0.92 | CYP2C9 (0.34) | CYP2C9PIK3CAMTORPIK3R1CYP3A4 | |
| SCHEMBL21596654 | 0.91 | PIK3CA (0.35) | CYP2C9PIK3CAMTORPIK3R1SGK1 | |
| SCHEMBL29829425 | 0.91 | PIK3CA (0.35) | CYP2C9PIK3CAMTORPIK3R1SGK1 | |
| SCHEMBL21596686 | 0.91 | PIK3CA (0.34) | CYP2C9PIK3CAMTORPIK3R1 | |
| SCHEMBL29829623 | 0.91 | PIK3CA (0.34) | CYP2C9PIK3CAMTORPIK3R1 | |
| SCHEMBL23610288 | 0.89 | PIK3CA (0.34) | CYP2C9PIK3CAMTORPIK3R1SGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469710-B | Pyridyl and pyrazinyl- (aza) indole sulfonamides | 优时比制药有限公司 | 2024-05-14 | — | — | CN | claimed |
| EP-3810591-B1 | PYRIDINYL AND PYRAZINYL-(AZA)INDOLSULFONAMIDES | UCB PHARMA GMBH (DE) | 2022-08-10 | — | — | EP | claimed |
| CN-112469710-B | Pyridyl and pyrazinyl- (aza) indole sulfonamides | 优时比制药有限公司 | 2024-05-14 | — | — | CN | disclosed |