SCHEMBL29831706

SCHEMBL29831706

Nc1ccc(-c2nc3ccc(N)cc3nc2-c2ccccc2)cc1

nearest known ligand 0.93

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.93
TLR9 Q9NR96 2/20 0.93
ATM Q13315 2/20 0.93
ALDH1A1 P00352 9/20 0.69
MEN1 O00255 7/20 0.69
MAPT P10636 6/20 0.69
LMNA P02545 3/20 0.69
GPR55 Q9Y2T6 1/20 0.69
PIK3CG P48736 1/20 0.63
KDM4E B2RXH2 7/20 0.58
L3MBTL1 Q9Y468 4/20 0.58
CYP3A4 P08684 3/20 0.56
CYP2C9 P11712 2/20 0.56
CYP2C19 P33261 2/20 0.56
TDP1 Q9NUW8 3/20 0.54
GAA P10253 5/20 0.53
HPGD P15428 5/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29831570 1.00 KMT2A (0.93) KMT2ATLR9ATMALDH1A1MEN1
SCHEMBL22288238 1.00 KMT2A (0.93) KMT2ATLR9ATMALDH1A1MEN1
SCHEMBL22288252 1.00 KMT2A (0.93) KMT2ATLR9ATMALDH1A1MEN1
SCHEMBL11792682 0.96 KMT2A (1.00) KMT2ATLR9ATMALDH1A1MEN1
SCHEMBL28041435 0.90 KMT2A (0.81) KMT2ATLR9ATMALDH1A1MEN1
SCHEMBL18082972 0.90 KMT2A (0.81) KMT2ATLR9ATMALDH1A1MEN1
SCHEMBL28041643 0.90 KMT2A (0.81) KMT2ATLR9ATMALDH1A1MEN1
SCHEMBL23384670 0.88 KMT2A (0.71) KMT2ATLR9ATMALDH1A1MEN1
SCHEMBL28044883 0.86 KMT2A (0.70) KMT2ATLR9ATMALDH1A1MEN1
SCHEMBL28044788 0.86 KMT2A (0.70) KMT2ATLR9ATMALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118027346-A Thermoplastic polyurethane elastomer material and preparation method thereof 四川轻化工大学 2024-05-14 CN disclosed
CN-112538053-B Method for synthesizing nitroquinoxaline or derivative thereof and aminoquinoxaline or derivative thereof 同济大学 2022-09-02 CN disclosed