Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRA | P18433 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | FDPS | P14324 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3472396 | 1.00 | PTPRA (0.61) | PTPRASMN1; SMN2CYP1A2CYP2D6MAPT | |
| SCHEMBL10065593 | 1.00 | PTPRA (0.61) | PTPRASMN1; SMN2CYP1A2CYP2D6MAPT | |
| SCHEMBL13972048 | 1.00 | PTPRA (0.61) | PTPRASMN1; SMN2CYP1A2CYP2D6MAPT | |
| SCHEMBL28625929 | 0.98 | PTPRA (0.59) | PTPRASMN1; SMN2CYP1A2CYP2D6MAPT | |
| Bromide SCHEMBL17476046 | 0.98 | PTPRA (0.59) | PTPRASMN1; SMN2CYP1A2CYP2D6MAPT | |
| Bromide SCHEMBL17476045 | 0.98 | PTPRA (0.59) | PTPRASMN1; SMN2CYP1A2CYP2D6MAPT | |
| SCHEMBL17642097 | 0.87 | PTPRA (0.53) | PTPRASMN1; SMN2CYP1A2CYP2D6MAPT | |
| SCHEMBL15075315 | 0.87 | PTPRA (0.53) | PTPRASMN1; SMN2CYP1A2CYP2D6MAPT | |
| SCHEMBL13957292 | 0.84 | PTPRA (0.58) | PTPRASMN1; SMN2CYP1A2CYP2D6MAPT | |
| SCHEMBL20272599 | 0.84 | PTPRA (0.58) | PTPRASMN1; SMN2CYP1A2CYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109369635-B | Compound or pharmaceutically acceptable salt thereof, application thereof and pharmaceutical composition | 赛克里翁治疗有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-109384778-B | Use of a compound or a pharmaceutically acceptable salt thereof for the manufacture of a medicament for the treatment of a disease, health condition or disorder | 赛克里翁治疗有限公司 | 2022-12-13 | — | — | CN | disclosed |
| CN-110016020-B | Compound or pharmaceutically acceptable salt thereof, application and pharmaceutical composition thereof | 赛克里翁治疗有限公司 | 2022-07-26 | — | — | CN | disclosed |