Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MTTP | P55157 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RORA | P35398 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | RORB | Q92753 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26108404 | 1.00 | CASR (0.40) | CASRSMN1; SMN2TLR8GAALMNA | |
| SCHEMBL26105278 | 0.84 | CASR (0.50) | CASRSMN1; SMN2TLR8GAALMNA | |
| SCHEMBL29832081 | 0.84 | CASR (0.50) | CASRSMN1; SMN2TLR8GAALMNA | |
| SCHEMBL26486207 | 0.81 | CASR (0.50) | CASRSMN1; SMN2TLR8GAA | |
| SCHEMBL26487228 | 0.81 | CASR (0.43) | CASRSMN1; SMN2TLR8GAALMNA | |
| SCHEMBL26109039 | 0.80 | CASR (0.50) | CASRSMN1; SMN2TLR8GAALMNA | |
| SCHEMBL29832214 | 0.80 | TLR8 (0.45) | CASRSMN1; SMN2TLR8GAALMNA | |
| SCHEMBL26107500 | 0.80 | TLR8 (0.45) | CASRSMN1; SMN2TLR8GAALMNA | |
| SCHEMBL29832612 | 0.80 | CASR (0.50) | CASRSMN1; SMN2TLR8GAALMNA | |
| SCHEMBL29831912 | 0.79 | MEN1 (0.43) | CASRSMN1; SMN2TLR8GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4298136-A1 | AMINO-BENZIMIDAZOLE CATALYSTS FOR THE PREPARATION OF POLYOLEFINS | Dow Global Technologies LLC (US) | 2024-01-03 | — | — | EP | disclosed |
| WO-2022183008-A9 | AMINO-BENZIMIDAZOLE CATALYSTS FOR THE PREPARATION OF POLYOLEFINS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2023-10-12 | — | — | WO | disclosed |
| WO-2022183008-A1 | AMINO-BENZIMIDAZOLE CATALYSTS FOR THE PREPARATION OF POLYOLEFINS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2022-09-01 | — | — | WO | disclosed |