Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.33 |
| ▸ | CTH | P32929 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18562081 | 0.73 | BRAF (0.41) | BRAFCTHPIK3CDMEN1KMT2A | |
| SCHEMBL20319063 | 0.71 | — | — | |
| SCHEMBL28761751 | 0.69 | BRAF (0.48) | BRAFROCK2KCNA5 | |
| SCHEMBL7243914 | 0.68 | MEN1 (0.44) | LMNAKCNA5MEN1KMT2A | |
| SCHEMBL6047182 | 0.68 | KCNA5 (0.57) | KCNH2BRAFKCNA5 | |
| SCHEMBL2037258 | 0.68 | BRAF (0.34) | BRAFSYKKCNA5 | |
| SCHEMBL30922284 | 0.68 | BRAF (0.34) | BRAFSYK | |
| SCHEMBL20037852 | 0.68 | BRAF (0.39) | BRAFSYKKCNA5 | |
| SCHEMBL30922270 | 0.68 | BRAF (0.34) | BRAFSYK | |
| SCHEMBL19325388 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022199589-A1 | PYRIMIDINE DERIVATIVES | 南京明德新药研发有限公司 | 2022-09-29 | — | — | WO | disclosed |