Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17785379 | 1.00 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL17785358 | 0.91 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL31339406 | 0.91 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL21145570 | 0.90 | KLKB1 (0.82) | KLKB1 | |
| SCHEMBL31339403 | 0.90 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL17785309 | 0.90 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL21145542 | 0.89 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL17785428 | 0.89 | KLKB1 (0.85) | KLKB1 | |
| SCHEMBL17785332 | 0.88 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL17785409 | 0.88 | KLKB1 (1.00) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4039681-A1 | N-((HET)ARYLMETHYL)-HETEROARYL-CARBOXAMIDES COMPOUNDS AS PLASMA KALLIKREIN INHIBITORS | Kalvista Pharmaceuticals Limited (GB) | 2022-08-10 | — | — | EP | disclosed |