Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 20/20 | 0.81 |
| ▸ | F11 | P03951 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17785305 | 1.00 | KLKB1 (0.81) | KLKB1F11 | |
| SCHEMBL17785353 | 0.90 | KLKB1 (0.80) | KLKB1F11 | |
| SCHEMBL17785367 | 0.89 | KLKB1 (1.00) | KLKB1F11 | |
| Hydrochloric Acid SCHEMBL17785323 | 0.88 | KLKB1 (0.93) | KLKB1F11 | |
| SCHEMBL17785436 | 0.81 | KLKB1 (0.79) | KLKB1 | |
| SCHEMBL17785319 | 0.78 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL17786924 | 0.78 | KLKB1 (0.62) | KLKB1F11 | |
| SCHEMBL17787151 | 0.75 | KLKB1 (0.65) | KLKB1F11 | |
| SCHEMBL17785396 | 0.75 | KLKB1 (0.84) | KLKB1F11 | |
| SCHEMBL20549483 | 0.74 | KLKB1 (0.70) | KLKB1F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4039681-A1 | N-((HET)ARYLMETHYL)-HETEROARYL-CARBOXAMIDES COMPOUNDS AS PLASMA KALLIKREIN INHIBITORS | Kalvista Pharmaceuticals Limited (GB) | 2022-08-10 | — | — | EP | disclosed |