SCHEMBL29836456

CC[C@H](C)[C@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CCC(N)=O)C(C)C)C(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)O)C(C)C

nearest known ligand 0.62

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	VIPR1	P32241	4/20	0.60

▸	VIPR2	P41587	6/20	0.57

▸	GLP1R	P43220	5/20	0.57

▸	GCGR	P47871	1/20	0.57

▸	GIPR	P48546	1/20	0.57

▸	BACE1	P56817	1/20	0.56

▸	TFPI	P10646	1/20	0.55

▸	CCKBR	P32239	1/20	0.55

▸	PTH1R	Q03431	2/20	0.54

▸	RXFP1	Q9HBX9	1/20	0.53

▸	ECE1	P42892	1/20	0.52

▸	MUS81	Q96NY9	1/20	0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29836409	0.99	VIPR1 (0.60)	VIPR1VIPR2GLP1RGCGRGIPR
SCHEMBL30168684	0.98	VIPR1 (0.60)	VIPR1VIPR2GLP1RGCGRGIPR
SCHEMBL30168738	0.97	VIPR1 (0.60)	VIPR1VIPR2GLP1RGCGRGIPR
SCHEMBL29836299	0.97	VIPR2 (0.58)	VIPR1VIPR2GLP1RGCGRGIPR
SCHEMBL29836306	0.95	VIPR2 (0.57)	VIPR1VIPR2GLP1RGCGRGIPR
SCHEMBL29836388	0.95	VIPR2 (0.61)	VIPR1VIPR2GLP1RGCGRGIPR
SCHEMBL30168745	0.95	VIPR2 (0.58)	VIPR1VIPR2GLP1RGCGRGIPR
SCHEMBL29836547	0.95	BACE1 (0.61)	VIPR1VIPR2GLP1RGCGRGIPR
SCHEMBL29836319	0.95	VIPR2 (0.56)	VIPR1VIPR2GLP1RGCGRGIPR
SCHEMBL29836415	0.94	BACE1 (0.62)	VIPR1VIPR2GLP1RGCGRGIPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-11434484-B2	Three-component CRISPR/Cas complex system and uses thereof	THE JACKSON LABORATORY (US)	2022-09-06	—	—	US	disclosed