Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MLYCD | O95822 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29836825 | 0.96 | MEN1 (0.92) | MEN1KMT2AHDAC6POLBHPGD | |
| SCHEMBL29032735 | 0.93 | MEN1 (0.86) | MEN1KMT2AHDAC6POLBHPGD | |
| SCHEMBL30450738 | 0.93 | MEN1 (0.86) | MEN1KMT2AHDAC6POLBHPGD | |
| SCHEMBL10722330 | 0.90 | MEN1 (0.81) | MEN1KMT2AHDAC6POLBALDH1A1 | |
| SCHEMBL29818100 | 0.86 | MEN1 (0.76) | MEN1KMT2AHDAC6POLBHPGD | |
| SCHEMBL21617139 | 0.86 | MEN1 (0.76) | MEN1KMT2AHDAC6POLBHPGD | |
| SCHEMBL21616933 | 0.84 | MEN1 (0.73) | MEN1KMT2AHDAC6POLBHPGD | |
| SCHEMBL30673997 | 0.84 | MEN1 (0.73) | MEN1KMT2AHDAC6POLBHPGD | |
| SCHEMBL22972218 | 0.84 | MEN1 (0.74) | MEN1KMT2AHDAC6POLBALDH1A1 | |
| SCHEMBL5967753 | 0.83 | MEN1 (0.71) | MEN1KMT2AHDAC6POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022157686-A1 | INHIBITORS OF ANOCTAMIN 6 PROTEIN AND USES THEREOF | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-07-28 | — | — | WO | disclosed |