Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 13/20 | 0.69 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.51 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.51 |
| ▸ | CLK1 | P49759 | 1/20 | 0.51 |
| ▸ | CLK2 | P49760 | 1/20 | 0.51 |
| ▸ | CLK3 | P49761 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.51 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.51 |
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.46 |
| ▸ | TTK | P33981 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21611024 | 1.00 | DYRK1A (0.69) | DYRK1ADYRK3CSNK1ECLK1CLK2 | |
| SCHEMBL21611038 | 0.93 | DYRK1A (0.69) | DYRK1ADYRK3CSNK1ECLK1CLK2 | |
| SCHEMBL21611066 | 0.87 | DYRK1A (0.80) | DYRK1ADYRK3CSNK1ECLK1CLK2 | |
| SCHEMBL29492983 | 0.87 | DYRK1A (0.80) | DYRK1ADYRK3CSNK1ECLK1CLK2 | |
| SCHEMBL21611052 | 0.82 | DYRK1A (1.00) | DYRK1ADYRK3CSNK1ECLK1CLK2 | |
| SCHEMBL29492968 | 0.82 | DYRK1A (1.00) | DYRK1ADYRK3CSNK1ECLK1CLK2 | |
| SCHEMBL29492976 | 0.81 | DYRK1A (0.85) | DYRK1ADYRK3CSNK1ECLK1CLK2 | |
| SCHEMBL21611037 | 0.81 | DYRK1A (0.85) | DYRK1ADYRK3CSNK1ECLK1CLK2 | |
| SCHEMBL21738308 | 0.79 | DYRK1A (0.62) | DYRK1ADYRK3CSNK1ECLK1CLK2 | |
| SCHEMBL21611057 | 0.78 | DYRK1A (0.84) | DYRK1ADYRK3CSNK1ECLK1CLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3604304-B1 | PYRROLO-PYRIDINE DERIVATIVE COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF PROTEIN KINASE-RELATED DISEASES | DAEGU GYEONGBUK MEDICAL INNOVATION FOUND (KR) | 2022-09-07 | — | — | EP | claimed |
| EP-3604304-B1 | PYRROLO-PYRIDINE DERIVATIVE COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF PROTEIN KINASE-RELATED DISEASES | DAEGU GYEONGBUK MEDICAL INNOVATION FOUND (KR) | 2022-09-07 | — | — | EP | disclosed |