Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | CD69 | Q07108 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23303962 | 1.00 | BTK (0.44) | BTKLCKCD69CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL31679740 | 0.99 | BTK (0.43) | BTKLCKCD69CYP3A4CYP2C9 | |
| SCHEMBL23303757 | 0.91 | BTK (0.44) | BTKLCK | |
| SCHEMBL23303998 | 0.90 | BTK (0.44) | BTKLCK | |
| SCHEMBL23303672 | 0.89 | BTK (0.51) | BTKLCKCYP2C9 | |
| SCHEMBL23303727 | 0.89 | BTK (0.44) | BTKLCKCD69 | |
| Hydrochloric Acid SCHEMBL31679718 | 0.88 | BTK (0.50) | BTKLCKCYP2C9 | |
| SCHEMBL23303781 | 0.88 | BTK (0.52) | BTKLCK | |
| SCHEMBL23303872 | 0.88 | BTK (0.41) | BTKLCK | |
| SCHEMBL29840442 | 0.88 | BTK (0.41) | BTKLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4051680-A1 | CONDENSED BI-HETEROCYCLES AS INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE | Biogen MA Inc. (US) | 2022-09-07 | — | — | EP | disclosed |