Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 18/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27217355 | 1.00 | TLR7 (0.60) | TLR7ADORA2ATLR8 | |
| SCHEMBL29840755 | 1.00 | TLR7 (0.60) | TLR7ADORA2ATLR8 | |
| SCHEMBL29840823 | 0.85 | TLR7 (0.69) | TLR7TLR8 | |
| SCHEMBL29840816 | 0.84 | TLR7 (0.58) | TLR7TLR8 | |
| SCHEMBL29840801 | 0.82 | TLR7 (0.68) | TLR7TLR8 | |
| SCHEMBL29840670 | 0.82 | TLR7 (0.60) | TLR7TLR8 | |
| SCHEMBL29840762 | 0.81 | TLR7 (0.67) | TLR7TLR8 | |
| Hydrochloric Acid SCHEMBL29840882 | 0.81 | TLR7 (0.59) | TLR7TLR8 | |
| SCHEMBL29840901 | 0.81 | TLR7 (0.63) | TLR7TLR8 | |
| SCHEMBL30663220 | 0.81 | TLR7 (0.66) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4288438-A1 | DERIVATIVES OF IMIDAZO[4,5-D]PYRIDAZINE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | Sanofi (FR) | 2023-12-13 | — | — | EP | disclosed |
| WO-2022167438-A1 | DERIVATIVES OF IMIDAZO[4,5-d]PYRIDAZINE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI (FR) | 2022-08-11 | — | — | WO | disclosed |