SCHEMBL29841673

SCHEMBL29841673

CCNc1cc(C2(Cc3nncn3C)CC(F)(F)C2)cc(N2Cc3c(cccc3C(F)(F)F)C2=O)n1

nearest known ligand 0.63

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30331741 0.84 CBLB (0.67) CBLB
SCHEMBL30331391 0.83 CBLB (0.66) CBLB
SCHEMBL30331735 0.83 CBLB (0.66) CBLB
SCHEMBL30331612 0.83 CBLB (0.65) CBLB
SCHEMBL21212747 0.83 CBLB (0.66) CBLB
SCHEMBL21200766 0.82 CBLB (0.86) CBLB
SCHEMBL21200287 0.82 CBLB (0.86) CBLB
SCHEMBL21200284 0.82 CBLB (0.86) CBLB
SCHEMBL29866920 0.82 CBLB (0.86) CBLB
SCHEMBL30331862 0.81 CBLB (0.69) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4288429-A1 LACTAMS AS CBL-B INHIBITORS Genentech, Inc. (US) 2023-12-13 — — EP disclosed
WO-2022169997-A1 LACTAMS AS CBL-B INHIBITORS GENENTECH, INC. (US) 2022-08-11 — — WO disclosed
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