Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGFR | P43088 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | ZAP70 | P43403 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23588255 | 1.00 | TSHR (0.46) | TSHRMAPK1TDP1ALDH1A1MAPT | |
| SCHEMBL23578293 | 0.83 | TSHR (0.38) | TSHRMAPK1TDP1ALDH1A1MAPT | |
| SCHEMBL29973191 | 0.83 | TSHR (0.38) | TSHRMAPK1TDP1ALDH1A1MAPT | |
| SCHEMBL29844162 | 0.83 | TSHR (0.62) | TSHRMAPK1TDP1ALDH1A1MAPT | |
| SCHEMBL23588088 | 0.83 | TSHR (0.62) | TSHRMAPK1TDP1ALDH1A1MAPT | |
| SCHEMBL25216596 | 0.81 | MAPT (0.48) | TSHRMAPK1TDP1ALDH1A1MAPT | |
| SCHEMBL29844221 | 0.80 | MAPK1 (0.49) | TSHRMAPK1TDP1ALDH1A1MAPT | |
| SCHEMBL23588364 | 0.80 | MAPK1 (0.49) | TSHRMAPK1TDP1ALDH1A1MAPT | |
| SCHEMBL23578213 | 0.80 | TSHR (0.49) | TSHRMAPK1TDP1ALDH1A1MAPT | |
| SCHEMBL23588168 | 0.79 | MAPT (0.40) | TSHRMAPK1TDP1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115066418-A | Carboxy derivatives with anti-inflammatory properties | 西特瑞治疗有限公司 | 2022-09-16 | — | — | CN | claimed |
| EP-4081511-A1 | CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES | Sitryx Therapeutics Limited (GB) | 2022-11-02 | — | — | EP | disclosed |
| CN-115066418-A | Carboxy derivatives with anti-inflammatory properties | 西特瑞治疗有限公司 | 2022-09-16 | — | — | CN | disclosed |