Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 9/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 9/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27186887 | 0.91 | KRAS (0.40) | KRASSOS1 | |
| SCHEMBL27186885 | 0.91 | KRAS (0.40) | KRASSOS1 | |
| SCHEMBL27186130 | 0.91 | SOS1 (0.39) | KRASSOS1 | |
| SCHEMBL27186125 | 0.91 | SOS1 (0.39) | KRASSOS1 | |
| SCHEMBL27186367 | 0.89 | SOS1 (0.36) | KRASSOS1 | |
| SCHEMBL27186234 | 0.89 | SOS1 (0.36) | KRASSOS1 | |
| SCHEMBL27186352 | 0.88 | KRAS (0.38) | KRASSOS1 | |
| SCHEMBL27186348 | 0.88 | KRAS (0.38) | KRASSOS1 | |
| SCHEMBL29168383 | 0.83 | KDM4E (0.30) | — | |
| SCHEMBL27186962 | 0.83 | KRAS (0.37) | KRASSOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022187266-A1 | NOVEL SUBSTITUTED BICYCLI AZA-HETEROCYCLES AS SOS1 INHIBITORS | VIVA STAR BIOSCIENCES (SUZHOU) CO., LTD. (CN) | 2022-09-09 | — | — | WO | disclosed |