Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.36 |
| ▸ | HTR2C | P28335 | 6/20 | 0.36 |
| ▸ | HTR2B | P41595 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23217252 | 1.00 | HTR2A (0.36) | HTR2AHTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL29845169 | 0.78 | HTR2A (0.35) | HTR2AHTR2CHTR2B | |
| SCHEMBL25033671 | 0.78 | HTR2A (0.35) | HTR2AHTR2CHTR2B | |
| SCHEMBL23217290 | 0.78 | HTR2A (0.35) | HTR2AHTR2CHTR2B | |
| SCHEMBL23227264 | 0.75 | HTR2C (0.49) | HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL29845008 | 0.74 | HTR2C (0.50) | HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL23217143 | 0.74 | HTR2C (0.50) | HTR2AHTR2CHTR2B | |
| SCHEMBL23217276 | 0.74 | HTR2A (0.35) | HTR2AHTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL23217177 | 0.71 | HTR2A (0.39) | HTR2AHTR2CHTR2B | |
| SCHEMBL29844903 | 0.71 | HTR2A (0.39) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041405-A1 | ARYL HETEROBICYCLIC COMPOUNDS AS KV1.3 POTASSIUM SHAKER CHANNEL BLOCKERS | D.E. Shaw Research, LLC (US) | 2022-08-17 | — | — | EP | disclosed |