Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 20/20 | 0.71 |
| ▸ | TLR8 | Q9NR97 | 20/20 | 0.71 |
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21062190 | 1.00 | TLR9 (0.71) | TLR9TLR8TLR7 | |
| SCHEMBL21062564 | 0.89 | TLR9 (0.72) | TLR9TLR8TLR7 | |
| SCHEMBL29844820 | 0.89 | TLR9 (0.72) | TLR9TLR8TLR7 | |
| SCHEMBL23066330 | 0.88 | TLR8 (0.70) | TLR9TLR8TLR7 | |
| SCHEMBL29844808 | 0.88 | TLR8 (0.70) | TLR9TLR8TLR7 | |
| SCHEMBL21062319 | 0.86 | TLR8 (0.68) | TLR9TLR8TLR7 | |
| SCHEMBL29844830 | 0.86 | TLR8 (0.68) | TLR9TLR8TLR7 | |
| SCHEMBL19952224 | 0.83 | TLR9 (1.00) | TLR9TLR8TLR7 | |
| SCHEMBL29584931 | 0.83 | TLR9 (1.00) | TLR9TLR8TLR7 | |
| SCHEMBL21062353 | 0.82 | TLR9 (0.59) | TLR9TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111527080-B | Substituted indole ether compounds | 百时美施贵宝公司 | 2023-09-22 | — | — | CN | claimed |
| EP-3724183-B1 | SUBSTITUTED INDOLE ETHER COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2022-08-17 | — | — | EP | claimed |
| CN-111527080-B | Substituted indole ether compounds | 百时美施贵宝公司 | 2023-09-22 | — | — | CN | disclosed |