Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 10/20 | 0.85 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.82 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.80 |
| ▸ | KDR | P35968 | 3/20 | 0.80 |
| ▸ | BTK | Q06187 | 5/20 | 0.72 |
| ▸ | JAK2 | O60674 | 3/20 | 0.69 |
| ▸ | BRD4 | O60885 | 1/20 | 0.69 |
| ▸ | JAK3 | P52333 | 5/20 | 0.65 |
| ▸ | JAK1 | P23458 | 1/20 | 0.64 |
| ▸ | TYK2 | P29597 | 1/20 | 0.64 |
| ▸ | BLK | P51451 | 1/20 | 0.63 |
| ▸ | BMX | P51813 | 1/20 | 0.63 |
| ▸ | FLT3 | P36888 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16514922 | 1.00 | EGFR (0.85) | EGFRFGFR2FGFR1KDRBTK | |
| Hydrochloric Acid SCHEMBL16513760 | 0.99 | EGFR (0.84) | EGFRFGFR2FGFR1KDRBTK | |
| Hydrochloric Acid SCHEMBL29847904 | 0.99 | EGFR (0.84) | EGFRFGFR2FGFR1KDRBTK | |
| Maleic Acid SCHEMBL29848267 | 0.96 | EGFR (0.79) | EGFRFGFR2FGFR1KDRBTK | |
| Maleic Acid SCHEMBL22464670 | 0.96 | EGFR (0.79) | EGFRFGFR2FGFR1KDRBTK | |
| Maleic Acid SCHEMBL16514642 | 0.96 | EGFR (0.79) | EGFRFGFR2FGFR1KDRBTK | |
| Fumaric Acid SCHEMBL16514646 | 0.96 | EGFR (0.79) | EGFRFGFR2FGFR1KDRBTK | |
| SCHEMBL16514042 | 0.93 | EGFR (0.73) | EGFRFGFR2FGFR1KDRBTK | |
| SCHEMBL29847829 | 0.93 | EGFR (0.73) | EGFRFGFR2FGFR1KDRBTK | |
| SCHEMBL29848454 | 0.92 | FGFR1 (0.79) | EGFRFGFR2FGFR1KDRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |