Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.70 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.66 |
| ▸ | KDR | P35968 | 2/20 | 0.66 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.61 |
| ▸ | GAK | O14976 | 1/20 | 0.59 |
| ▸ | FES | P07332 | 1/20 | 0.59 |
| ▸ | FER | P16591 | 1/20 | 0.59 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.59 |
| ▸ | TEC | P42680 | 1/20 | 0.59 |
| ▸ | CLK1 | P49759 | 1/20 | 0.59 |
| ▸ | JAK3 | P52333 | 1/20 | 0.59 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.59 |
| ▸ | BTK | Q06187 | 1/20 | 0.59 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.59 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16514385 | 1.00 | EGFR (0.70) | EGFRFGFR1KDRFGFR2GAK | |
| SCHEMBL16515004 | 0.91 | FGFR1 (0.70) | EGFRFGFR1KDRFGFR2GAK | |
| SCHEMBL20787671 | 0.91 | FGFR1 (0.70) | EGFRFGFR1KDRFGFR2GAK | |
| SCHEMBL16513999 | 0.91 | EGFR (0.78) | EGFRFGFR1KDRFGFR2GAK | |
| SCHEMBL29847561 | 0.90 | FGFR1 (0.81) | EGFRFGFR1KDRFGFR2GAK | |
| SCHEMBL16513796 | 0.90 | FGFR1 (0.81) | EGFRFGFR1KDRFGFR2GAK | |
| SCHEMBL16514225 | 0.89 | FGFR1 (0.70) | EGFRFGFR1KDRFGFR2JAK3 | |
| SCHEMBL29847661 | 0.89 | FGFR1 (0.70) | EGFRFGFR1KDRFGFR2JAK3 | |
| SCHEMBL16514731 | 0.88 | FGFR1 (0.67) | EGFRFGFR1KDRFGFR2JAK3 | |
| SCHEMBL16514278 | 0.88 | EGFR (0.71) | EGFRFGFR1KDRFGFR2ERBB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |