Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.84 |
| ▸ | KDR | P35968 | 3/20 | 0.84 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.84 |
| ▸ | EGFR | P00533 | 9/20 | 0.73 |
| ▸ | JAK3 | P52333 | 5/20 | 0.53 |
| ▸ | BTK | Q06187 | 1/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16514365 | 1.00 | FGFR1 (0.84) | FGFR1KDRFGFR2EGFRJAK3 | |
| Fumaric Acid SCHEMBL16514197 | 0.96 | FGFR1 (0.79) | FGFR1KDRFGFR2EGFRJAK3 | |
| Maleic Acid SCHEMBL26980891 | 0.96 | FGFR1 (0.79) | FGFR1KDRFGFR2EGFRJAK3 | |
| Maleic Acid SCHEMBL16514196 | 0.96 | FGFR1 (0.79) | FGFR1KDRFGFR2EGFRJAK3 | |
| SCHEMBL16514255 | 0.93 | FGFR1 (0.72) | FGFR1KDRFGFR2EGFRJAK3 | |
| SCHEMBL16514084 | 0.93 | FGFR1 (0.72) | FGFR1KDRFGFR2EGFRJAK3 | |
| SCHEMBL29848110 | 0.93 | FGFR1 (0.72) | FGFR1KDRFGFR2EGFRJAK3 | |
| SCHEMBL16513520 | 0.91 | FGFR1 (0.89) | FGFR1KDRFGFR2EGFRJAK3 | |
| Rx-518 SCHEMBL16514522 | 0.91 | FGFR2 (1.00) | FGFR1KDRFGFR2EGFRJAK3 | |
| Rx-518 SCHEMBL29369343 | 0.91 | FGFR2 (1.00) | FGFR1KDRFGFR2EGFRJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |