Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 4/20 | 0.62 |
| ▸ | JAK3 | P52333 | 3/20 | 0.62 |
| ▸ | CCND3 | P30281 | 2/20 | 0.60 |
| ▸ | CDK2 | P24941 | 2/20 | 0.60 |
| ▸ | CCNK | O75909 | 1/20 | 0.60 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.60 |
| ▸ | CDK9 | P50750 | 1/20 | 0.60 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.60 |
| ▸ | EGFR | P00533 | 1/20 | 0.59 |
| ▸ | BRD4 | O60885 | 1/20 | 0.57 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.53 |
| ▸ | JUN | P05412 | 1/20 | 0.53 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.53 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.53 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.53 |
| ▸ | TTK | P33981 | 3/20 | 0.51 |
| ▸ | CDK4 | P11802 | 2/20 | 0.51 |
| ▸ | CCND1 | P24385 | 2/20 | 0.51 |
| ▸ | CCND2 | P30279 | 1/20 | 0.51 |
| ▸ | SYK | P43405 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16514118 | 1.00 | JAK2 (0.62) | JAK2JAK3CCND3CDK2CCNK | |
| SCHEMBL16513586 | 0.91 | EGFR (0.59) | JAK2JAK3CCND3CDK2CCNK | |
| SCHEMBL16513819 | 0.91 | EGFR (0.59) | JAK2JAK3CCND3CDK2CCNK | |
| SCHEMBL29848021 | 0.91 | EGFR (0.59) | JAK2JAK3CCND3CDK2CCNK | |
| SCHEMBL29847649 | 0.91 | EGFR (0.59) | JAK2JAK3CCND3CDK2CCNK | |
| SCHEMBL16513502 | 0.90 | CCND3 (0.65) | JAK2JAK3CCND3CDK2CCNK | |
| SCHEMBL16513933 | 0.90 | CDK2 (0.58) | JAK2JAK3CCND3CDK2CCNK | |
| SCHEMBL21155529 | 0.87 | CDK2 (0.68) | JAK2JAK3CCND3CDK2CCNK | |
| SCHEMBL16513575 | 0.85 | CCND3 (0.57) | JAK2JAK3CCND3CDK2CCNK | |
| SCHEMBL29576058 | 0.84 | JAK2 (0.63) | JAK2JAK3CCND3EGFRBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |