Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 3/20 | 0.61 |
| ▸ | PLK4 | O00444 | 5/20 | 0.55 |
| ▸ | JUN | P05412 | 5/20 | 0.55 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.55 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.55 |
| ▸ | TTK | P33981 | 1/20 | 0.51 |
| ▸ | SYK | P43405 | 1/20 | 0.50 |
| ▸ | IGF1R | P08069 | 2/20 | 0.49 |
| ▸ | CDK1 | P06493 | 2/20 | 0.49 |
| ▸ | CDK4 | P11802 | 2/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.49 |
| ▸ | CCND1 | P24385 | 2/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.49 |
| ▸ | CDK2 | P24941 | 2/20 | 0.49 |
| ▸ | JAK3 | P52333 | 1/20 | 0.49 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16514866 | 1.00 | JAK2 (0.61) | JAK2PLK4JUNMAPK8MAPK10 | |
| SCHEMBL29847068 | 0.90 | JAK2 (0.48) | JAK2PLK4JUNMAPK8MAPK10 | |
| SCHEMBL16514279 | 0.90 | JAK2 (0.48) | JAK2PLK4JUNMAPK8MAPK10 | |
| SCHEMBL16513407 | 0.90 | BRD4 (0.59) | JAK2CDK4CCND1CDK2JAK3 | |
| SCHEMBL16514324 | 0.90 | CDK2 (0.50) | JAK2PLK4JUNMAPK8MAPK10 | |
| SCHEMBL29847654 | 0.90 | CDK2 (0.50) | JAK2PLK4JUNMAPK8MAPK10 | |
| SCHEMBL29848216 | 0.90 | BRD4 (0.59) | JAK2CDK4CCND1CDK2JAK3 | |
| SCHEMBL16515714 | 0.87 | JAK2 (0.51) | JAK2JUNMAPK8MAPK10CDK4 | |
| SCHEMBL16514799 | 0.86 | JAK2 (0.66) | JAK2PLK4JUNMAPK8MAPK10 | |
| SCHEMBL29847962 | 0.86 | MAPK10 (0.61) | JAK2PLK4JUNMAPK8MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |