Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.81 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.78 |
| ▸ | BTK | Q06187 | 7/20 | 0.72 |
| ▸ | JAK2 | O60674 | 4/20 | 0.70 |
| ▸ | JAK1 | P23458 | 4/20 | 0.70 |
| ▸ | JAK3 | P52333 | 4/20 | 0.70 |
| ▸ | TYK2 | P29597 | 2/20 | 0.70 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.67 |
| ▸ | KDR | P35968 | 2/20 | 0.67 |
| ▸ | TTK | P33981 | 1/20 | 0.62 |
| ▸ | FLT3 | P36888 | 1/20 | 0.61 |
| ▸ | BLK | P51451 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16513980 | 1.00 | EGFR (0.81) | EGFRFGFR2BTKJAK2JAK1 | |
| SCHEMBL16514767 | 0.97 | EGFR (0.76) | EGFRFGFR2BTKJAK2JAK1 | |
| SCHEMBL29848265 | 0.97 | EGFR (0.76) | EGFRFGFR2BTKJAK2JAK1 | |
| SCHEMBL21449167 | 0.96 | EGFR (0.75) | EGFRFGFR2BTKJAK2JAK1 | |
| SCHEMBL29847929 | 0.92 | EGFR (0.69) | EGFRFGFR2BTKJAK2JAK1 | |
| SCHEMBL16513694 | 0.92 | EGFR (0.69) | EGFRFGFR2BTKJAK2JAK1 | |
| SCHEMBL16513826 | 0.92 | EGFR (0.82) | EGFRFGFR2BTKJAK2JAK1 | |
| SCHEMBL29848128 | 0.92 | EGFR (0.82) | EGFRFGFR2BTKJAK2JAK1 | |
| SCHEMBL16515011 | 0.92 | BTK (0.70) | EGFRFGFR2BTKJAK2JAK1 | |
| SCHEMBL16514701 | 0.91 | EGFR (0.68) | EGFRFGFR2BTKJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |