Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 6/20 | 0.76 |
| ▸ | EGFR | P00533 | 8/20 | 0.66 |
| ▸ | JAK3 | P52333 | 6/20 | 0.66 |
| ▸ | JAK2 | O60674 | 2/20 | 0.66 |
| ▸ | BLK | P51451 | 1/20 | 0.66 |
| ▸ | BMX | P51813 | 1/20 | 0.66 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.64 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.62 |
| ▸ | KDR | P35968 | 1/20 | 0.62 |
| ▸ | SRC | P12931 | 2/20 | 0.61 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.61 |
| ▸ | JAK1 | P23458 | 1/20 | 0.60 |
| ▸ | TYK2 | P29597 | 1/20 | 0.60 |
| ▸ | FLT3 | P36888 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16514136 | 1.00 | BTK (0.76) | BTKEGFRJAK3JAK2BLK | |
| SCHEMBL16513752 | 0.92 | EGFR (0.78) | BTKEGFRJAK3JAK2BLK | |
| SCHEMBL29847877 | 0.92 | EGFR (0.78) | BTKEGFRJAK3JAK2BLK | |
| SCHEMBL16513688 | 0.91 | BTK (0.75) | BTKEGFRJAK3JAK2BLK | |
| SCHEMBL29848247 | 0.91 | BTK (0.75) | BTKEGFRJAK3JAK2BLK | |
| SCHEMBL16514405 | 0.91 | BTK (0.69) | BTKEGFRJAK3JAK2BLK | |
| SCHEMBL29847638 | 0.91 | BTK (0.69) | BTKEGFRJAK3JAK2BLK | |
| SCHEMBL16513723 | 0.91 | BTK (0.62) | BTKEGFRJAK3JAK2BLK | |
| SCHEMBL29848055 | 0.91 | BTK (0.62) | BTKEGFRJAK3JAK2BLK | |
| SCHEMBL16513731 | 0.91 | FGFR1 (0.69) | BTKEGFRJAK3JAK2BLK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |