Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.82 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.71 |
| ▸ | KDR | P35968 | 3/20 | 0.71 |
| ▸ | JAK3 | P52333 | 6/20 | 0.66 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.66 |
| ▸ | BTK | Q06187 | 3/20 | 0.64 |
| ▸ | JAK2 | O60674 | 2/20 | 0.56 |
| ▸ | BLK | P51451 | 1/20 | 0.56 |
| ▸ | BMX | P51813 | 1/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.54 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16514170 | 1.00 | EGFR (0.82) | EGFRFGFR1KDRJAK3FGFR2 | |
| SCHEMBL16513862 | 0.92 | EGFR (0.81) | EGFRFGFR1KDRJAK3FGFR2 | |
| SCHEMBL29847855 | 0.92 | EGFR (0.81) | EGFRFGFR1KDRJAK3FGFR2 | |
| SCHEMBL16513561 | 0.91 | FGFR2 (0.81) | EGFRFGFR1KDRJAK3FGFR2 | |
| SCHEMBL16514316 | 0.90 | FGFR2 (0.70) | EGFRFGFR1KDRJAK3FGFR2 | |
| SCHEMBL16513909 | 0.90 | EGFR (1.00) | EGFRFGFR1KDRJAK3FGFR2 | |
| SCHEMBL29847724 | 0.90 | EGFR (0.79) | EGFRFGFR1KDRJAK3FGFR2 | |
| SCHEMBL16513691 | 0.90 | EGFR (0.79) | EGFRFGFR1KDRJAK3FGFR2 | |
| SCHEMBL16514045 | 0.90 | EGFR (0.79) | EGFRFGFR1KDRJAK3FGFR2 | |
| SCHEMBL29847155 | 0.90 | EGFR (0.79) | EGFRFGFR1KDRJAK3FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |