SCHEMBL29848741

SCHEMBL29848741

Cn1cc(-c2ccc(F)c(N)c2)c2ccccc2c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 19/20 1.00
BRD9 Q9H8M2 1/20 0.56
BRD7 Q9NPI1 1/20 0.56
BRDT Q58F21 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16650720 1.00 BRD4 (1.00) BRD4BRD9BRD7BRDT
Hydrochloric Acid SCHEMBL29848853 0.99 BRD4 (0.97) BRD4BRD9BRD7BRDT
Hydrochloric Acid SCHEMBL16651302 0.99 BRD4 (0.97) BRD4BRD9BRD7BRDT
SCHEMBL19857684 0.84 BRD4 (0.72) BRD4BRD9BRD7BRDT
SCHEMBL29613205 0.84 BRD4 (0.72) BRD4BRD9BRD7BRDT
SCHEMBL29848755 0.81 BRD4 (1.00) BRD4BRD9BRD7
SCHEMBL16651105 0.81 BRD4 (1.00) BRD4BRD9BRD7
Hydrochloric Acid SCHEMBL16651039 0.80 BRD4 (0.97) BRD4BRD9BRD7
Hydrochloric Acid SCHEMBL29848868 0.80 BRD4 (0.97) BRD4BRD9BRD7
SCHEMBL15893960 0.79 BRD4 (0.74) BRD4BRD9BRD7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240182490-A1 BROMODOMAIN INHIBITORS CELGENE QUANTICEL RESEARCH, INC. (US) 2024-06-06 US disclosed
US-11884680-B2 Bromodomain inhibitors CELGENE QUANTICEL RESEARCH, INC. (US) 2024-01-30 US disclosed
EP-4134364-A2 BROMODOMAIN INHIBITORS Celgene Quanticel Research, Inc. (US) 2023-02-15 EP disclosed
US-20220315601-A1 BROMODOMAIN INHIBITORS CELGENE QUANTICEL RESEARCH, INC. (US) 2022-10-06 US disclosed
EP-3640241-B1 BROMODOMAIN INHIBITORS CELGENE QUANTICEL RES INC (US) 2022-09-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240182490-A1 BROMODOMAIN INHIBITORS BRD3, EP300, BRPF3 BRD4 5/4885BRD9 19/4885BRD7 14/4885
US-20220315601-A1 BROMODOMAIN INHIBITORS BRD3, EP300, BRPF3 BRD4 5/4885BRD9 19/4885BRD7 14/4885
US-11884680-B2 Bromodomain inhibitors BRD3, EP300, BRPF3 BRD4 5/4885BRD9 19/4885BRD7 14/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.