SCHEMBL29848792

SCHEMBL29848792

Cn1ccnc1-c1cn(C)c(=O)c2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 17/20 1.00
▸ BRD9 Q9H8M2 2/20 0.54
▸ BRD7 Q9NPI1 2/20 0.54
▸ L3MBTL1 Q9Y468 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16651272 1.00 BRD4 (1.00) BRD4BRD9BRD7L3MBTL1
SCHEMBL16651456 0.78 BRD4 (1.00) BRD4BRD9BRD7L3MBTL1
SCHEMBL29849051 0.78 BRD4 (1.00) BRD4BRD9BRD7L3MBTL1
SCHEMBL16650475 0.75 BRD4 (1.00) BRD4BRD9BRD7L3MBTL1
SCHEMBL29848915 0.75 BRD4 (1.00) BRD4BRD9BRD7L3MBTL1
SCHEMBL5486071 0.73 HTR2C (0.66) BRD4L3MBTL1
Hydrochloric Acid SCHEMBL4345829 0.73 BRD4 (0.57) BRD4L3MBTL1
SCHEMBL29848807 0.72 BRD4 (1.00) BRD4BRD9BRD7L3MBTL1
SCHEMBL16651178 0.72 BRD4 (1.00) BRD4BRD9BRD7L3MBTL1
SCHEMBL13587950 0.72 BRD4 (0.56) BRD4L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240182490-A1 BROMODOMAIN INHIBITORS CELGENE QUANTICEL RESEARCH, INC. (US) 2024-06-06 — — US disclosed
US-11884680-B2 Bromodomain inhibitors CELGENE QUANTICEL RESEARCH, INC. (US) 2024-01-30 — — US disclosed
US-20220315601-A1 BROMODOMAIN INHIBITORS CELGENE QUANTICEL RESEARCH, INC. (US) 2022-10-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240182490-A1 BROMODOMAIN INHIBITORS BRD3, EP300, BRPF3 BRD4 5/4885BRD9 19/4885BRD7 14/4885
US-20220315601-A1 BROMODOMAIN INHIBITORS BRD3, EP300, BRPF3 BRD4 5/4885BRD9 19/4885BRD7 14/4885
US-11884680-B2 Bromodomain inhibitors BRD3, EP300, BRPF3 BRD4 5/4885BRD9 19/4885BRD7 14/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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