Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24671627 | 1.00 | SOS1 (0.65) | SOS1KRAS | |
| SCHEMBL29849179 | 1.00 | SOS1 (0.65) | SOS1KRAS | |
| SCHEMBL24671638 | 1.00 | SOS1 (0.65) | SOS1KRAS | |
| SCHEMBL24672124 | 0.85 | SOS1 (0.52) | SOS1KRAS | |
| SCHEMBL24671974 | 0.84 | SOS1 (0.67) | SOS1KRAS | |
| SCHEMBL29849210 | 0.84 | SOS1 (0.52) | SOS1KRAS | |
| SCHEMBL29849127 | 0.84 | SOS1 (0.52) | SOS1KRAS | |
| SCHEMBL24583652 | 0.82 | SOS1 (0.62) | SOS1KRAS | |
| SCHEMBL23259912 | 0.82 | SOS1 (0.56) | SOS1KRAS | |
| SCHEMBL29863172 | 0.82 | SOS1 (0.56) | SOS1KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022170802-A1 | PYRIMIDO-PYRIDONE DERIVATIVE AS SOS1 INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州阿尔脉生物科技有限公司 | 2022-08-18 | — | — | WO | disclosed |