Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL3 | P20749 | 6/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.76 |
| ▸ | GAA | P10253 | 1/20 | 0.76 |
| ▸ | POLB | P06746 | 1/20 | 0.73 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16430957 | 1.00 | BCL3 (0.82) | BCL3ALDH1A1GAAPOLBCD274 | |
| SCHEMBL29849958 | 0.91 | POLB (0.87) | BCL3ALDH1A1GAAPOLBCD274 | |
| SCHEMBL16430973 | 0.91 | POLB (0.87) | BCL3ALDH1A1GAAPOLBCD274 | |
| SCHEMBL17870596 | 0.90 | BCL3 (1.00) | BCL3ALDH1A1GAAPOLBCD274 | |
| SCHEMBL17554108 | 0.89 | BCL3 (0.73) | BCL3ALDH1A1GAAPOLBCD274 | |
| SCHEMBL17554020 | 0.89 | BCL3 (0.76) | BCL3ALDH1A1GAAPOLBCD274 | |
| SCHEMBL17554174 | 0.89 | BCL3 (0.76) | BCL3ALDH1A1GAAPOLBCD274 | |
| SCHEMBL29849769 | 0.89 | BCL3 (0.85) | BCL3ALDH1A1GAAPOLBKMT2A | |
| SCHEMBL16431055 | 0.89 | BCL3 (0.85) | BCL3ALDH1A1GAAPOLBKMT2A | |
| SCHEMBL17554112 | 0.88 | BCL3 (0.64) | BCL3ALDH1A1GAAPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3027594-B1 | 2-BENZOYLAMINOBENZAMIDE DERIVATIVES AS BCL-3 INHIBITORS | UNIV COLLEGE CARDIFF CONSULTANTS LTD (GB) | 2022-08-10 | — | — | EP | claimed |
| EP-3027594-B1 | 2-BENZOYLAMINOBENZAMIDE DERIVATIVES AS BCL-3 INHIBITORS | UNIV COLLEGE CARDIFF CONSULTANTS LTD (GB) | 2022-08-10 | — | — | EP | disclosed |