SCHEMBL2985183

SCHEMBL2985183

C=C(C(=O)O)C(C)(C)CC(N)O

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 4/20 0.36
GRIK1 P39086 2/20 0.33
GRIK2 Q13002 1/20 0.33
GRM1 Q13255 1/20 0.33
GRM2 Q14416 1/20 0.33
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
PTGS1 P23219 1/20 0.31
TET3 O43151 1/20 0.30
TET1 Q8NFU7 1/20 0.30
SLC7A5 Q01650 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2992949 0.80 ACACB (0.35) TET2GRIK1GRIK2GRM1GRM2
SCHEMBL2994453 0.76 GRIK1 (0.31) TET2GRIK1GRIK2GRM1GRM2
SCHEMBL15936370 0.75 GABRR1 (0.35) TET2TET3TET1SLC7A5
SCHEMBL1135248 0.73 KDM4E (0.39) TET2
SCHEMBL2138939 0.70 TET2 (0.38) TET2ALDH1A1
SCHEMBL1963590 0.70 TET2 (0.38) TET2ALDH1A1
SCHEMBL132663 0.70 TET2 (0.34) TET2
SCHEMBL3775748 0.69 TET2 (0.37) TET2
SCHEMBL28357690 0.69 TET2 (0.37) TET2
SCHEMBL9346344 0.69 TET2 (0.37) TET2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100170650-A1 Printability improving agents and papers coated with them NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2010-07-08 US disclosed
US-20080023163-A1 Printability Improving Agents And Papers Coated With Them NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2008-01-31 US disclosed