Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4152078 | 0.83 | KLKB1 (0.37) | DGAT1PTGS2MAPT | |
| SCHEMBL25414258 | 0.82 | SMN1; SMN2 (0.41) | DGAT1TDP1SMN1; SMN2POLBRAB9A | |
| SCHEMBL30871782 | 0.81 | TDP1 (0.45) | DGAT1TDP1SMN1; SMN2POLBIDO1 | |
| SCHEMBL25107980 | 0.81 | TDP1 (0.40) | DGAT1TDP1SMN1; SMN2POLBRAB9A | |
| SCHEMBL30414625 | 0.80 | F2RL1 (0.38) | DGAT1TDP1SMN1; SMN2POLBIDO1 | |
| SCHEMBL20854943 | 0.80 | TDP1 (0.40) | DGAT1TDP1SMN1; SMN2POLBCYP2C9 | |
| SCHEMBL31021743 | 0.80 | SMN1; SMN2 (0.41) | DGAT1TDP1SMN1; SMN2POLBIDO1 | |
| SCHEMBL24298797 | 0.80 | TDP1 (0.39) | DGAT1TDP1SMN1; SMN2POLBRAB9A | |
| SCHEMBL17593262 | 0.80 | TDP1 (0.39) | DGAT1TDP1SMN1; SMN2POLBIDO1 | |
| SCHEMBL20140164 | 0.80 | TDP1 (0.39) | DGAT1TDP1SMN1; SMN2POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929676-A | Heterocyclic carboxylate compounds as glycolate oxidase inhibitors | 紫丁香疗法有限公司 | 2022-08-19 | — | — | CN | disclosed |