Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 7/20 | 0.56 |
| ▸ | MKNK2 | Q9HBH9 | 7/20 | 0.56 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.44 |
| ▸ | PIM1 | P11309 | 2/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 3/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23294594 | 1.00 | MKNK1 (0.56) | MKNK1MKNK2KMOHAO1PIM1 | |
| SCHEMBL29852332 | 1.00 | MKNK1 (0.56) | MKNK1MKNK2KMOHAO1PIM1 | |
| SCHEMBL23294359 | 1.00 | MKNK1 (0.56) | MKNK1MKNK2KMOHAO1PIM1 | |
| SCHEMBL29852321 | 0.93 | MKNK1 (0.49) | MKNK1MKNK2KMOHAO1PIM1 | |
| SCHEMBL23294505 | 0.93 | MKNK1 (0.49) | MKNK1MKNK2KMOHAO1PIM1 | |
| SCHEMBL23294375 | 0.86 | MAP2K4 (0.45) | HAO1DHODHALDH1A1CYP1A2 | |
| SCHEMBL23294477 | 0.86 | MAP2K4 (0.45) | HAO1DHODHALDH1A1CYP1A2 | |
| SCHEMBL23328966 | 0.84 | MAP2K4 (0.41) | HAO1 | |
| SCHEMBL23294401 | 0.83 | HAO1 (0.45) | MKNK1HAO1DHODHALDH1A1 | |
| SCHEMBL15946998 | 0.83 | KDM4E (0.46) | HAO1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929676-B | Heterocyclic carboxylate compounds as glycolate oxidase inhibitors | 紫丁香疗法有限公司 | 2025-04-29 | — | — | CN | disclosed |
| CN-114929676-A | Heterocyclic carboxylate compounds as glycolate oxidase inhibitors | 紫丁香疗法有限公司 | 2022-08-19 | — | — | CN | disclosed |