Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL483689 | 1.00 | TLR7 (0.85) | TLR7TLR8 | |
| SCHEMBL728467 | 0.95 | TLR7 (0.84) | TLR7TLR8 | |
| SCHEMBL3973102 | 0.94 | TLR7 (0.82) | TLR7TLR8 | |
| SCHEMBL3975772 | 0.94 | TLR7 (0.82) | TLR7TLR8 | |
| SCHEMBL3970575 | 0.93 | TLR7 (0.81) | TLR7TLR8 | |
| SCHEMBL3972423 | 0.92 | TLR7 (0.79) | TLR7TLR8 | |
| Cpg-52852 SCHEMBL483385 | 0.92 | TLR7 (1.00) | TLR7TLR8 | |
| Cpg-52852 SCHEMBL29371102 | 0.92 | TLR7 (1.00) | TLR7TLR8 | |
| SCHEMBL2743937 | 0.91 | TLR7 (0.80) | TLR7TLR8 | |
| SCHEMBL3970939 | 0.90 | TLR7 (0.70) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4531910-A2 | CHEMICAL SCREEN OF MODULATORS FOR VACCINE ADJUVANTS | The University of Chicago (US) | 2025-04-09 | — | — | EP | disclosed |
| CN-119136795-A | Conjugates of small molecule immunopotentiators as adjuvants with enhanced efficacy and reduced toxicity of NFKB activators | 芝加哥大学 | 2024-12-13 | — | — | CN | disclosed |
| EP-4429655-A1 | SMALL MOLECULE IMMUNOPOTENTIATOR CONJUGATES OF NFKB ACTIVATORS AS ADJUVANTS WITH ENHANCED EFFICACY AND REDUCED TOXICITY | The University of Chicago (US) | 2024-09-18 | — | — | EP | disclosed |
| CN-118475357-A | Immunotherapy for the treatment of cancer | 俄亥俄州创新基金会 | 2024-08-09 | — | — | CN | disclosed |
| WO-2023235771-A2 | CHEMICAL SCREEN OF MODULATORS FOR VACCINE ADJUVANTS | THE UNIVERSITY OF CHICAGO (US) | 2023-12-07 | — | — | WO | disclosed |
| WO-2023086806-A1 | COMPOSITIONS AND METHODS FOR INDUCING IMMUNE TOLERANCE | THE UNIVERSITY OF CHICAGO (US) | 2023-05-19 | — | — | WO | disclosed |
| WO-2023086890-A1 | SMALL MOLECULE IMMUNOPOTENTIATOR CONJUGATES OF NFKB ACTIVATORS AS ADJUVANTS WITH ENHANCED EFFICACY AND REDUCED TOXICITY | THE UNIVERSITY OF CHICAGO (US) | 2023-05-19 | — | — | WO | disclosed |
| EP-4166572-A1 | ANTI-PD-1 ANTIBODIES AND METHODS OF USE THEREOF | Rinat Neuroscience Corp. (US) | 2023-04-19 | — | — | EP | disclosed |
| EP-4090336-A1 | TOLL-LIKE RECEPTOR AGONIST FORMULATIONS AND METHODS OF USE | The University of Chicago (US) | 2022-11-23 | — | — | EP | disclosed |
| EP-3230319-B1 | ANTI-PD-1 ANTIBODIES AND METHODS OF USE THEREOF | RINAT NEUROSCIENCE CORP (US) | 2022-09-07 | — | — | EP | disclosed |
| US-20220249657-A1 | ANTI-PD-1 ANTIBODIES AND METHODS OF USE THEREOF | RINAT NEUROSCIENCE CORP. (US) | 2022-08-11 | — | — | US | disclosed |