Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8269479 | 1.00 | DPP4 (0.70) | DPP4 | |
| SCHEMBL8271510 | 0.81 | DPP4 (1.00) | DPP4 | |
| SCHEMBL8294400 | 0.79 | DPP4 (0.75) | DPP4 | |
| SCHEMBL8271511 | 0.79 | DPP4 (1.00) | DPP4 | |
| SCHEMBL8271515 | 0.77 | DPP4 (1.00) | DPP4 | |
| SCHEMBL13205203 | 0.77 | DPP4 (1.00) | DPP4 | |
| SCHEMBL8271512 | 0.77 | DPP4 (1.00) | DPP4 | |
| Hydrochloric Acid SCHEMBL2973326 | 0.76 | DPP4 (1.00) | DPP4 | |
| Hydrochloric Acid SCHEMBL2973270 | 0.75 | DPP4 (1.00) | DPP4 | |
| SCHEMBL8295868 | 0.74 | DPP4 (0.79) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7786163-B2 | Constrained cyano compounds | Forest Laboratories Holdings Limited (BM) | 2010-08-31 | — | — | US | claimed |
| EP-1778220-A1 | CONSTRAINED CYANO COMPOUNDS | Phenomix Corporation (US) | 2007-05-02 | — | — | EP | claimed |
| WO-2006017292-A1 | CONSTRAINED CYANO COMPOUNDS | PHENOMIX CORPORATION (US) | 2006-02-16 | — | — | WO | claimed |
| US-20060009518-A1 | Constrained cyano compounds | Forest Laboratories Holding Limited (BM) | 2006-01-12 | — | — | US | claimed |
| US-7786163-B2 | Constrained cyano compounds | Forest Laboratories Holdings Limited (BM) | 2010-08-31 | — | — | US | disclosed |
| US-20060009518-A1 | Constrained cyano compounds | Forest Laboratories Holding Limited (BM) | 2006-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060009518-A1 | Constrained cyano compounds | DNPEP, PREP, PEPD | DPP4 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.