Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | MTTP | P55157 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23288057 | 1.00 | RXFP1 (0.42) | RXFP1MLYCDSMOHDAC8KLKB1 | |
| SCHEMBL24962230 | 0.93 | RXFP1 (0.41) | RXFP1MLYCDSMOHDAC8KLKB1 | |
| SCHEMBL29857221 | 0.92 | MTTP (0.38) | RXFP1HDAC8HSD11B1NR1H4SLC6A2 | |
| SCHEMBL23228021 | 0.92 | MTTP (0.38) | RXFP1HDAC8HSD11B1NR1H4SLC6A2 | |
| SCHEMBL23227788 | 0.91 | HDAC8 (0.37) | HDAC8HSD11B1SLC6A2SLC6A4AKR1C3 | |
| SCHEMBL30370622 | 0.91 | HDAC8 (0.37) | HDAC8HSD11B1SLC6A2SLC6A4AKR1C3 | |
| SCHEMBL24962227 | 0.91 | HDAC8 (0.37) | RXFP1HDAC8HSD11B1NR1H4SLC6A2 | |
| SCHEMBL29857236 | 0.91 | HDAC8 (0.38) | RXFP1HDAC8NR1H4SLC6A2SLC6A4 | |
| SCHEMBL23227807 | 0.91 | HDAC8 (0.38) | RXFP1HDAC8NR1H4SLC6A2SLC6A4 | |
| SCHEMBL23251050 | 0.90 | RXFP1 (0.40) | RXFP1HDAC8HSD11B1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112707841-B | 3-N-cyclopropylmethyl-2-fluorobenzamide compound and preparation method and application thereof | 南通泰禾化工股份有限公司 | 2022-08-23 | — | — | CN | disclosed |