Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.41 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.39 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.39 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.37 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26916829 | 1.00 | KMT2A (0.43) | KMT2AHTTKEAP1PIK3CDPIK3CB | |
| SCHEMBL19480882 | 0.82 | CYP2A6 (0.46) | KMT2AKEAP1PIK3CDPIK3CBPIK3CG | |
| SCHEMBL25295400 | 0.81 | MAPK10 (0.37) | KMT2AKEAP1ADORA2AJMJD6NPC1 | |
| SCHEMBL30509979 | 0.81 | MAPK10 (0.37) | KMT2AKEAP1ADORA2AJMJD6NPC1 | |
| SCHEMBL19480880 | 0.81 | ATR (0.42) | KMT2AKEAP1PIK3CDPIK3CBPIK3CG | |
| SCHEMBL17203633 | 0.77 | KMT2A (0.43) | KMT2AHTTPIK3CDPIK3CBPIK3CG | |
| SCHEMBL26917043 | 0.77 | PIK3CD (0.41) | KMT2AKEAP1PIK3CDPIK3CBPIK3CG | |
| SCHEMBL17203227 | 0.76 | KMT2A (0.42) | KMT2AHTTPIK3CDPIK3CBPIK3CG | |
| SCHEMBL28983677 | 0.75 | PIK3CD (0.42) | KMT2AKEAP1PIK3CDPIK3CBPIK3CG | |
| SCHEMBL30177024 | 0.75 | PIK3CD (0.42) | KMT2AKEAP1PIK3CDPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4288437-A1 | MAP4K1 INHIBITORS | Bayer Aktiengesellschaft (DE) | 2023-12-13 | — | — | EP | disclosed |
| WO-2022167627-A1 | MAP4K1 INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-08-11 | — | — | WO | disclosed |