SCHEMBL29858892

SCHEMBL29858892

COc1ccc(C2COc3cc(C(N)=O)ccc3O2)cn1

nearest known ligand 0.67

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 18/20 0.67
NNMT P40261 1/20 0.50
MKNK1 Q9BUB5 1/20 0.46
MKNK2 Q9HBH9 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18397159 1.00 CSF1R (0.67) CSF1RNNMTMKNK1MKNK2
SCHEMBL18397023 0.90 CSF1R (0.60) CSF1R
SCHEMBL29858956 0.90 CSF1R (0.60) CSF1R
SCHEMBL18397164 0.90 CSF1R (0.60) CSF1R
SCHEMBL29859308 0.90 CSF1R (0.60) CSF1R
SCHEMBL18397240 0.89 CSF1R (0.61) CSF1R
SCHEMBL29859027 0.89 CSF1R (0.61) CSF1R
SCHEMBL18397406 0.85 CSF1R (0.56) CSF1R
SCHEMBL29859723 0.85 CSF1R (0.56) CSF1R
SCHEMBL21588139 0.85 CSF1R (0.56) CSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107922396-B Colony stimulating factor-1 receptor (CSF-1R) inhibitors 建新公司 2022-08-05 CN disclosed