Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 8/20 | 1.00 |
| ▸ | KDR | P35968 | 3/20 | 0.43 |
| ▸ | BRAF | P15056 | 3/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | RAF1 | P04049 | 3/20 | 0.40 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18396998 | 1.00 | CSF1R (1.00) | CSF1RKDRBRAFMAPK14RAF1 | |
| SCHEMBL18397285 | 0.88 | CSF1R (1.00) | CSF1RKDRBRAFMAPK14RAF1 | |
| SCHEMBL29859417 | 0.88 | CSF1R (1.00) | CSF1RKDRBRAFMAPK14RAF1 | |
| SCHEMBL18397186 | 0.78 | CSF1R (0.83) | CSF1RKDR | |
| SCHEMBL29859212 | 0.76 | CSF1R (1.00) | CSF1RKDRPDGFRBKIT | |
| SCHEMBL18397338 | 0.76 | CSF1R (1.00) | CSF1RKDRPDGFRBKIT | |
| SCHEMBL18397118 | 0.70 | CSF1R (0.52) | CSF1R | |
| SCHEMBL12391452 | 0.69 | KDR (0.59) | CSF1RKDRBRAFMAPK14RAF1 | |
| SCHEMBL6427214 | 0.69 | KDR (0.59) | CSF1RKDRBRAFMAPK14RAF1 | |
| SCHEMBL19149350 | 0.68 | KDR (0.58) | CSF1RKDRBRAFMAPK14RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922396-B | Colony stimulating factor-1 receptor (CSF-1R) inhibitors | 建新公司 | 2022-08-05 | — | — | CN | disclosed |