Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 8/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.35 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18397041 | 1.00 | CSF1R (0.62) | CSF1RMEN1KMT2AL3MBTL1NTRK1 | |
| SCHEMBL18397190 | 0.87 | CSF1R (0.61) | CSF1RMEN1KMT2AL3MBTL1NTRK1 | |
| SCHEMBL30918145 | 0.81 | CSF1R (0.55) | CSF1RMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL29859315 | 0.80 | CSF1R (0.51) | CSF1RNTRK1NTRK2KIT | |
| SCHEMBL18397394 | 0.80 | CSF1R (0.51) | CSF1RNTRK1NTRK2KIT | |
| SCHEMBL29859212 | 0.77 | CSF1R (1.00) | CSF1RKITKDM4E | |
| SCHEMBL18397204 | 0.77 | CSF1R (0.84) | CSF1RKMT2AKDM4E | |
| SCHEMBL18397338 | 0.77 | CSF1R (1.00) | CSF1RKITKDM4E | |
| SCHEMBL18397186 | 0.76 | CSF1R (0.83) | CSF1RTRPC6 | |
| SCHEMBL19461724 | 0.76 | CSF1R (0.46) | CSF1RCALM1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922396-B | Colony stimulating factor-1 receptor (CSF-1R) inhibitors | 建新公司 | 2022-08-05 | — | — | CN | disclosed |