Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 19/20 | 0.65 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23263117 | 1.00 | WEE1 (0.65) | WEE1SIK2CYP3A4 | |
| SCHEMBL29859410 | 0.95 | WEE1 (0.69) | WEE1SIK2CYP3A4 | |
| SCHEMBL23263115 | 0.95 | WEE1 (0.69) | WEE1SIK2CYP3A4 | |
| SCHEMBL21373451 | 0.94 | WEE1 (0.68) | WEE1SIK2CYP3A4 | |
| SCHEMBL29506539 | 0.94 | WEE1 (0.68) | WEE1SIK2CYP3A4 | |
| SCHEMBL29859347 | 0.92 | WEE1 (0.78) | WEE1CYP3A4 | |
| SCHEMBL23246115 | 0.92 | WEE1 (0.78) | WEE1CYP3A4 | |
| SCHEMBL21373325 | 0.91 | WEE1 (0.69) | WEE1SIK2CYP3A4 | |
| SCHEMBL29506460 | 0.91 | WEE1 (0.69) | WEE1SIK2CYP3A4 | |
| SCHEMBL21373392 | 0.91 | WEE1 (0.63) | WEE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117202908-A | Use of Wee1 kinase inhibitors in the treatment of cancer diseases | 上海瑛派药业有限公司 | 2023-12-08 | — | — | CN | claimed |
| WO-2023093840-A1 | USE OF WEE1 KINASE INHIBITORS IN THE TREATMENT OF CANCER | IMPACT THERAPEUTICS (SHANGHAI) , INC (CN) | 2023-06-01 | — | — | WO | claimed |
| WO-2022188802-A1 | USE OF WEE1 KINASE INHIBITORS IN THE TREATMENT OF CANCER | IMPACT THERAPEUTICS (SHANGHAI) , INC (CN) | 2022-09-15 | — | — | WO | claimed |
| CN-117202908-A | Use of Wee1 kinase inhibitors in the treatment of cancer diseases | 上海瑛派药业有限公司 | 2023-12-08 | — | — | CN | disclosed |
| WO-2023093840-A1 | USE OF WEE1 KINASE INHIBITORS IN THE TREATMENT OF CANCER | IMPACT THERAPEUTICS (SHANGHAI) , INC (CN) | 2023-06-01 | — | — | WO | disclosed |
| WO-2022188802-A1 | USE OF WEE1 KINASE INHIBITORS IN THE TREATMENT OF CANCER | IMPACT THERAPEUTICS (SHANGHAI) , INC (CN) | 2022-09-15 | — | — | WO | disclosed |