Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9490223 | 0.89 | TDP1 (0.61) | TDP1LMNAMAPK1HIF1ASLC6A2 | |
| SCHEMBL296938 | 0.88 | TDP1 (0.78) | TDP1LMNAMAPK1HIF1ASLC6A2 | |
| SCHEMBL9189899 | 0.88 | TDP1 (0.85) | TDP1LMNAMAPK1HIF1ASLC6A2 | |
| Ethylene SCHEMBL9928862 | 0.87 | TDP1 (0.76) | TDP1LMNAMAPK1HIF1ASLC6A2 | |
| Ethylene SCHEMBL8622525 | 0.87 | TDP1 (0.76) | TDP1LMNAMAPK1HIF1ASLC6A2 | |
| Ethylene SCHEMBL11578922 | 0.87 | TDP1 (0.76) | TDP1LMNAMAPK1HIF1ASLC6A2 | |
| Ethylene SCHEMBL7587624 | 0.87 | TDP1 (0.76) | TDP1LMNAMAPK1HIF1ASLC6A2 | |
| SCHEMBL137486 | 0.87 | TDP1 (0.83) | TDP1LMNAMAPK1HIF1ASLC6A2 | |
| SCHEMBL789219 | 0.86 | TDP1 (0.81) | TDP1LMNAMAPK1HIF1ASLC6A2 | |
| SCHEMBL9341245 | 0.86 | TDP1 (0.73) | TDP1LMNAMAPK1HIF1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 808 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143002-A | Preparation method of indolinyl acetone | 浙江工业大学 | 2023-12-01 | — | — | CN | claimed |
| CN-116621756-A | Preparation method of 3, 3-difluoro-gamma-lactam compound | 遵义医科大学 | 2023-08-22 | — | — | CN | claimed |
| WO-2023079554-A1 | CHEMICALLY MODIFIED MULTIFUNCTIONAL INORGANIC PARTICLES | THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI INSTITUTE) (IL) | 2023-05-11 | — | — | WO | claimed |
| CN-107075121-B | Polysiloxane copolymers or terpolymers and polymers made therefrom | 莫门蒂夫性能材料股份有限公司 | 2021-01-22 | — | — | CN | claimed |
| CN-106496092-B | It is a kind of for synthesizing the preparation method of the intermediate of silodosin | 江苏宇田医药有限公司 | 2019-03-29 | — | — | CN | claimed |
| CN-108250086-A | The improvement synthetic method of one kind (R) -1- aryl -2- propylamine | 中山大学 | 2018-07-06 | — | — | CN | claimed |
| CN-105254553-B | The preparation method of Silodosin intermediate | 黄欢 | 2018-04-10 | — | — | CN | claimed |
| CN-106380438-A | Preparation method of indoline derivative for synthesizing silodosin | 江苏宇田医药有限公司 | 2017-02-08 | — | — | CN | claimed |
| CN-105254553-A | Method for preparing silodosin midbody | HUANG HUAN | 2016-01-20 | — | — | CN | claimed |
| CN-103396352-B | Preparation method of Silodosin | SUZHOU PTECHNOLOGY CO LTD | 2015-04-08 | — | — | CN | claimed |
| EP-0766670-B1 | TRI-SUBSTITUTED PHENYL DERIVATIVES USEFUL AS PDE IV INHIBITORS | CELLTECH R&D LTD (GB) | 2002-03-27 | — | — | EP | claimed |
| US-5530128-A | ENZYME INHIBITOR AS ANTITUMOR AGENT | CELLTECH THERAPEUTICS LIMITED (GB) | 1996-06-25 | — | — | US | claimed |
| CN-1094027-A | The benzoyl-acrylic acid di-esters contains their pharmaceutical composition and prepares their method | RICHTER GEDEON VEGYESZET (HU) | 1994-10-26 | — | — | CN | claimed |
| US-5329016-A | Antianxiety, hypnotic agents, antiepileptic agents or nootropics | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-07-12 | — | — | US | claimed |
| US-5175162-A | Anxiolytic, antiepilepic agents | YOSHITIOMI PHARMACEUTICAL INDUSTRIES LTD. (JP) | 1992-12-29 | — | — | US | claimed |
| EP-0152379-A2 | Process for preparing pharmaceutical compositions containing unilamellar liposomes | CIBA-GEIGY AG (CH) | 1985-08-21 | — | — | EP | claimed |
| US-4450109-A | VASODILATION; CARDIOTONIC AGENTS; HYPOTENSIVE AGENTS | SS PHARMACEUTICAL CO., LTD. (JP) | 1984-05-22 | — | — | US | claimed |
| US-4315855-A | Monoazo disperse dyes containing a nitrophenyl group and a homophthalimide group | BASF AKTIENGESELLSCHAFT (DE) | 1982-02-16 | — | — | US | claimed |
| US-4264494-A | Chromium complex dyestuffs for natural polyamides and synthetic nylons | BASF AKTIENGESELLSCHAFT (DE) | 1981-04-28 | — | — | US | claimed |
| US-4212801-A | Unsymmetrical 1:2-chromium complexes containing an azo and an azomethine bond | BASF AKTIENGESELLSCHAFT (DE) | 1980-07-15 | — | — | US | claimed |