Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 17/20 | 1.00 |
| ▸ | KRAS | P01116 | 4/20 | 0.48 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23326486 | 1.00 | SOS1 (1.00) | SOS1KRASCNR1CNR2 | |
| SCHEMBL23326487 | 1.00 | SOS1 (1.00) | SOS1KRASCNR1CNR2 | |
| SCHEMBL23326597 | 0.89 | SOS1 (1.00) | SOS1KRAS | |
| SCHEMBL29543059 | 0.89 | SOS1 (1.00) | SOS1KRAS | |
| SCHEMBL23326596 | 0.89 | SOS1 (1.00) | SOS1KRAS | |
| SCHEMBL23326353 | 0.80 | SOS1 (1.00) | SOS1 | |
| SCHEMBL23326355 | 0.80 | SOS1 (1.00) | SOS1 | |
| SCHEMBL23326423 | 0.79 | SOS1 (1.00) | SOS1KRAS | |
| SCHEMBL23326421 | 0.79 | SOS1 (1.00) | SOS1KRAS | |
| SCHEMBL29861660 | 0.79 | SOS1 (1.00) | SOS1KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116425742-A | Bicyclic heteroaryl compounds and uses thereof | 锐新医药公司 | 2023-07-14 | — | — | CN | disclosed |
| EP-4055017-A1 | BICYCLIC HETEROARYL COMPOUNDS AND USES THEREOF | Revolution Medicines, Inc. (US) | 2022-09-14 | — | — | EP | disclosed |
| CN-114901662-A | Bicyclic heteroaryl compounds and uses thereof | 锐新医药公司 | 2022-08-12 | — | — | CN | disclosed |