SCHEMBL29861472

SCHEMBL29861472

CC(=O)N1CCC(c2cc3c(NC(C)c4cc(C(F)(F)F)cc(N)n4)ncnc3n(C)c2=O)CC1

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SOS1 Q07889 20/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23326388 1.00 SOS1 (0.77) SOS1
SCHEMBL23345150 1.00 SOS1 (0.77) SOS1
SCHEMBL23326859 0.88 SOS1 (0.75) SOS1
SCHEMBL29861803 0.88 SOS1 (0.75) SOS1
SCHEMBL23326860 0.88 SOS1 (0.75) SOS1
SCHEMBL23345116 0.87 SOS1 (1.00) SOS1
SCHEMBL23326726 0.86 SOS1 (1.00) SOS1
SCHEMBL29542936 0.86 SOS1 (1.00) SOS1
SCHEMBL23326725 0.86 SOS1 (1.00) SOS1
SCHEMBL23326368 0.81 SOS1 (1.00) SOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116425742-A Bicyclic heteroaryl compounds and uses thereof 锐新医药公司 2023-07-14 CN disclosed
EP-4055017-A1 BICYCLIC HETEROARYL COMPOUNDS AND USES THEREOF Revolution Medicines, Inc. (US) 2022-09-14 EP disclosed
CN-114901662-A Bicyclic heteroaryl compounds and uses thereof 锐新医药公司 2022-08-12 CN disclosed