Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31129761 | 0.77 | NPC1 (0.38) | NPC1DGAT1 | |
| SCHEMBL30470561 | 0.75 | NPC1 (0.39) | NPC1MAPTDGAT1 | |
| SCHEMBL29324119 | 0.75 | NPC1 (0.39) | NPC1MAPTDGAT1 | |
| SCHEMBL14800179 | 0.75 | NPC1 (0.42) | NPC1MAPTDGAT1 | |
| SCHEMBL32659805 | 0.74 | NPC1 (0.38) | NPC1MAPTDGAT1 | |
| SCHEMBL30645867 | 0.73 | NPC1 (0.40) | NPC1MAPTDGAT1 | |
| SCHEMBL32674400 | 0.73 | NPC1 (0.34) | NPC1DGAT1 | |
| SCHEMBL31638938 | 0.72 | NPC1 (0.39) | NPC1MAPTDGAT1 | |
| SCHEMBL637196 | 0.71 | NPC1 (0.42) | NPC1MAPTDGAT1 | |
| SCHEMBL29081529 | 0.71 | NPC1 (0.40) | NPC1MAPTDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4304727-A1 | EGFR INHIBITORS | Blueprint Medicines Corporation (US) | 2024-01-17 | — | — | EP | disclosed |
| WO-2022192431-A1 | EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2022-09-15 | — | — | WO | disclosed |