Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 11/20 | 0.40 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23459165 | 1.00 | CHRM2 (0.53) | CHRM2CHRM1CHRM5CHRM3HSD11B1 | |
| SCHEMBL23459162 | 1.00 | CHRM2 (0.53) | CHRM2CHRM1CHRM5CHRM3HSD11B1 | |
| SCHEMBL23744125 | 0.90 | CHRM2 (0.48) | CHRM2CHRM1CHRM5CHRM3HSD11B1 | |
| SCHEMBL23459168 | 0.88 | CHRM2 (0.54) | CHRM2CHRM1CHRM5CHRM3HSD11B1 | |
| SCHEMBL23459164 | 0.88 | CHRM2 (0.54) | CHRM2CHRM1CHRM5CHRM3HSD11B1 | |
| SCHEMBL23459171 | 0.88 | CHRM2 (0.54) | CHRM2CHRM1CHRM5CHRM3HSD11B1 | |
| Hydrochloric Acid SCHEMBL23459169 | 0.87 | CHRM2 (0.53) | CHRM2CHRM1CHRM5CHRM3HSD11B1 | |
| SCHEMBL29862138 | 0.83 | CHRM2 (0.50) | CHRM2CHRM1CHRM5CHRM3HSD11B1 | |
| SCHEMBL29861845 | 0.83 | CHRM2 (0.50) | CHRM2CHRM1CHRM5CHRM3HSD11B1 | |
| SCHEMBL18231725 | 0.78 | CHRM2 (0.43) | CHRM2CHRM1CHRM5CHRM3SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4069367-A1 | MUSCARINIC RECEPTOR 4 ANTAGONISTS AND METHODS OF USE | Neurocrine Biosciences, Inc. (US) | 2022-10-12 | — | — | EP | disclosed |