SCHEMBL29862250

SCHEMBL29862250

Cc1cc(C)c(-n2ccn(-c3c(C)cc(C)cc3C)c2=[Ru](Cl)(Cl)=Cc2ccccc2)c(C)c1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
CRHBP P24387 1/20 0.30
KMT2A Q03164 1/20 0.30
CRHR2 Q13324 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
NFE2L2 Q16236 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1942951 0.75 BACE1 (0.32)
SCHEMBL7178485 0.72
SCHEMBL15388072 0.70
SCHEMBL7534345 0.70 MEN1 (0.31) MEN1LMNAMAPTCRHBPKMT2A
SCHEMBL4650164 0.70 BACE1 (0.31)
SCHEMBL15189782 0.69
SCHEMBL15512414 0.67 PSMB5 (0.32)
SCHEMBL17685647 0.67 C5AR1 (0.30)
SCHEMBL1535723 0.67 BACE1 (0.31)
SCHEMBL31518989 0.63 PTGS1 (0.35) LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4077465-A1 ADHESIVE ARTICLE COMPRISING POLYMER AND POLYMERIZABLE CYCLIC OLEFINS, ADHESIVE COMPOSITIONS AND METHODS 3M Innovative Properties Company (US) 2022-10-26 EP disclosed
WO-2022219427-A1 COMPOSITIONS COMPRISING CYCLIC OLEFINS AND THERMALLY CONDUCTIVE FILLER AND ADHESION PROMOTER 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-10-20 WO disclosed
EP-4045560-A1 COMPOSITIONS COMPRISING CYCLIC OLEFINS AND THERMALLY CONDUCTIVE FILLER 3M Innovative Properties Company (US) 2022-08-24 EP disclosed